Is a Gluten-Free Diet Enough to Control the Complications of Celiac Disease?
A lifelong gluten-free diet (GFD) is the conventional approach to managing
celiac disease, a chronic inflammatory disorder affecting the small intestine
that can result in malnutrition. However, recent evidence shows that a
GFD may not be sufficient to prevent serious complications related to
celiac disease. A detailed discussion of the metabolic disorders and functional
abnormalities that can develop, and nutritional treatments for these is
presented in a Review article published in
Journal of Medicinal Food
, a peer-reviewed journal from
Mary Ann Liebert, Inc., publishers. The article is available free on the
Journal of Medicinal Food website until October 2, 2014.
Sara Farnetti and coauthors, Catholic University of the Sacred Heart (Rome, Italy),
cover a broad scope of digestive and nutrient absorptive processes in
individuals with celiac disease that may be compromised due to increased
inflammation. In the article “
Functional and Metabolic Disorders in Celiac Disease: New Implications
for Nutritional Treatment,” the authors discuss how diminished gallbladder and pancreatic
function, and increased gut permeability may contribute to the development
of overweight and obesity, and impaired glucose and lipid metabolism and
insulin secretion in these patients.
“This article reviews the extensive literature on lifelong gluten-free
diet supplementation to celiac disease patients and makes outstanding
recommendations,” says
Journal of Medicinal Food
Editor-in-Chief
Sampath Parthasarathy, MBA, PhD, Florida Hospital Chair in Cardiovascular Sciences, University of Central
Florida, Orlando. “The authors conclude that plant oils and products
are able to stimulate the gall bladder to promote the absorption process
and provide better nutrition to these patients. The conclusion that a
lifelong gluten-free diet provision must be accompanied by proper nutrient
supplementation is a sound one; however, caution must be exercised in
using fried oil as a gall bladder stimulant.”
About the Journal
Journal of Medicinal Food
is an authoritative, peer-reviewed, multidisciplinary journal published
monthly in print and online. Led by Editors-in-Chief
Sampath Parthasarathy, MBA, PhD, and
Young-Eun Lee, PhD, Wonkwang University, Jeonbuk, Korea, this scientific journal publishes
original research on the bioactive substances of functional and medicinal
foods, nutraceuticals, herbal substances, and other natural products.
The Journal explores the chemistry and biochemistry of these substances,
as well as the methods for their extraction and analysis, the use of biomarkers
and other methods to assay their biological roles, and the development
of bioactive substances for commercial use. Tables of content and a sample
issue may be viewed on the
Journal of Medicinal Food
website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing
authoritative peer-reviewed journals in many promising areas of science
and biomedical research, including
The Journal of Alternative and Complementary Medicine. Its biotechnology trade magazine,
Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry’s most
widely read publication worldwide. A complete list of the firm’s
80 journals, books, and newsmagazines is available on the
Mary Ann Liebert, Inc., publishers
website.